Revista de Osteoporosis y Metabolismo Mineral

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Citescore: 1,06 |  Academic Accelerator: 0,194 
SCImago Journal Rank : 0,12 | Google Scholar: 0,0172

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Author: Romm

Pathophysiology of osteoporosis in chronic inflammatory joint diseases

Chronic inflammation is a nonspecific response against aggressor agents mediated by the body’s immune system. In such a scenario, an infiltrate of predominantly mononuclear cells, such as lymphocytes, macrophages and plasma cells, is produced. Under certain conditions or when the aggressor agent persists, a sustainable accumulation and activation of immune cells occurs. Then, the secretion of cytokines, agents that prolong the life of lymphocytes and macrophages, is increased, what leads to chronic inflammation.
Inflammation is the main mechanism involved in bone destruction in chronic inflammatory diseases (CIDs) [1], such as rheumatoid arthritis (RA), ankylosing spondylitis (AS), psoriatic arthritis (PsA), systemic lupus erythematosus (SLE), multiple sclerosis and/or inflammatory bowel disease (IBD). These diseases show a chronic systemic inflammation that can affect different organs, caused by an alteration of the immune system [2].

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Unusual case of bone proliferation: Nora’s lesion

We present the case of a 43-year-old man who presents pain and functional impotence in the left wrist of one year of evolution. Upon examination, an indurated tumor adhered to deep planes is found in this location. Following findings on computerized axial tomography (CT) of images consistent with osteochondroma versus peripheral chondrosarcoma (Figure 1), a bone scan was requested. This bone scintigraphic study in three phases of the upper limbs and a subsequent full-body image (Figure 2), showed the early arrival of the tracer with an increase in the vascular pool of slight-moderate intensity in the distal portion of the left radius (arrow), which persisted with greater intensity in late images. No other diseased findings were observed in the rest of the skeleton. These findings revealed increased vascularity and osteoblastic activity at the distal end of the left radius.
A biopsy was carry out, with a pathological result of osteochondromatous proliferation compatible with Nora’s lesion, confirming this diagnosis after surgical resection.

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Care profile of susceptible patients with osteoporosis by telemedicine visits in the post-COVID-19 era

Osteoporotic fractures represent a growing public health problem worldwide. At present, we lack adequate procedures for prevention, diagnosis, assessment, intervention and patient follow-up.
New technologies have provided new communication tools and have changed our mentality, with the possibility of carrying out, virtually, actions or procedures in our daily lives that until now required our physical presence, either for technical, cultural or social reasons [1].
The COVID-19 pandemic, caused by the SARS-COV-2 virus, has triggered a global public health emergency with rapid evolution and tragic consequences. The fight against this disease is forcing to modify the forms of care, which includes transforming some face-to-face consultations into remote ones [2].
Prior to the COVID-19 pandemic, telemedicine, in its different forms, was used in exceptional situations. One of the first uses was the tele-nursing practice that emerged in the UK and Canada at a primary care level.

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Are femoral bone mass measurements symmetrical?

This issue of the journal offers an interesting article on possible differences in femur densitometry related to the dominance of the upper extremities between left and right handed [1].
Dual-energy X-ray absorptiometry (DXA) is based on the measurement of areal bone mineral density centimeter (BMD, g/cm2) in the proximal femur and lumbar spine. Conditions such as osteoarthritis or osteophytic calcifications influence spinal BMD and confer a great value to femoral measurement. Since the DXA technique began being used on the hips, the presumption that there may be a minimal bilateral asymmetry between the proximal femurs has been maintained, but with no clinical relevance. Several research groups have studied this question. It has not been established whether there are systematic differences between the BMD of both hips, and in order to answer the questions: is the bone density in one of the femurs similar to same in the opposite side? which of them to choose?

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Comparison of the femur proximal extremity’s densitometric values in young and healthy study participants: left-handed vs. right-handed

Dual-energy X-ray absorptiometry, commonly known as bone densitometry [1], is a technic broadly used in daily clinical practice and is considered the gold standard to estimate the bone mineral density (BMD) [1-4]. When performing a densitometry, the values obtained, usually in the lumbar spine and in the proximal extremity of the femur, are compared with the reference values for the population of each country, so the T-score and Z-score values can be calculated [3-5]. By consensus, the World Health Organization recommended the osteoporosis densitometric diagnosis to be carried out in the presence of a T-score value lower than -2.5 of the typical deviation of the peak BMD [2]. Although this criterion has been a topic for controversy, it has also become a world reference that has allowed the homogenisation of the randomized trials, among other advantages [1-6].

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Solo mostrar coincidencias exactas
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Buscar en cuerpo de texto
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Filtrar por categorías
11
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120191101-en
120191102-en
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120211301-en
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920191101-en
Clinical Notes
Committees
Editorial
English
Index of Authors
Index of Communications
Letter to the Director
Oral Communications
Original Articles
Osteology images
Position Paper
Poster Communications
Presentation
Reviews
SIBOMM News
Special Article
Special Documents

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